Republican Sen. Lindsey Graham said Thursday he won’t vote for Supreme Court nominee Ketanji Brown Jackson, expressing concerns about her record despite supporting her confirmation as an appeals court judge last year.

The South Carolina senator’s announcement had been expected after he criticized Jackson during her four days of hearings last week. But it gives Democrats one less Republican vote as they seek bipartisan backing for President Joe Biden’s pick to replace retiring Justice Stephen Breyer.

Graham, Sen. Susan Collins of Maine and Sen. Lisa Murkowski of Alaska were the only three Republicans to vote to confirm Jackson on the appeals court in 2021. Collins announced Wednesday that she’ll vote for Jackson’s Supreme Court nomination, as well, giving Democrats at least one GOP vote. Murkowski has said she’s still undecided.

A final confirmation vote is expected next week. Jackson would be the first Black woman on the high court in its more than 200-year history, and the sixth woman.

In a speech on the Senate floor, Graham said his decision is based partly on what he sees as a “flawed sentencing methodology regarding child pornography cases,” echoing a line of questioning by some Republicans on the Senate Judiciary Committee last week. Several senators, some eyeing a run for president, repeatedly asked her about her sentencing decisions in her nine years as a federal judge in an effort to paint her as too lenient on sex criminals.